What this site is for

It exists to separate what is established about polynucleotide injectables from what is claimed, and to grade each honestly rather than presenting the class as settled in either direction. That is why every claim is placed in one of three groups, why regulatory status is reported as its own question rather than as a finding about the material, and why the size and funding of the studies behind each claim are stated alongside it.

What it deliberately does not do

It does not recommend for or against treatment, and it does not invite a reader toward an assessment or a consultation. It is not a booking page and it offers no service in relation to anything it describes. It does not name brands of products, does not quote prices or dosages, and does not present one product as the safe choice or as a dangerous one on the strength of a marketing sentence.

The facts kept visible

Three facts are repeated wherever they are relevant. The material is a purified DNA-fragment gel and the name describes its contents rather than an effect on your DNA. The published work behind the skin-quality, under-eye and hair claims is small, short and concentrated in a few centres, so each claim is graded separately. And long-term behaviour is unmeasured, which is different from established and different from disproven.

How the content is reviewed and corrected

Ke He, MD, Deputy Director and Head of Skin & Laser Aesthetics, is the responsible physician. This subject moves on a faster clock than most, because a product’s regulatory route can change without any new research being published, so the review is dated and revisited on a short cycle rather than treated as a settled text. If you find something unclear, out of date or wrong, the contact page explains how to tell us, and the correction is made to the page itself.